For R&D use only.

Telmisartan

  • Catalog NO.:A808270
  • CAS No. : 144701-48-4
  • Molecular Formula:C33H30N4O2
  • Molecular Weight: 514.62
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Quality Control&SDS
SDS COA NMR

Product Details

CAS Number 144701-48-4 Appearance Off-white powder
Catalog Number A808270 MDL Number MFCD00918125
Molecular Formula C33H30N4O2 Molecular Weight 514.62
Boiling Point Melting Point 265-277°C
Flash Point Density
Synonyms 2-[4-[[4-methyl-6-(1-methylbenzimidazol-2-yl)-2-propyl-benzimidazol-1-yl]methyl]phenyl]benzoic acid
Storage Condition Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word Warning UN Number Not hazmat
Hazard Statements H315; H319; H335 Class
Precautionary Statements P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501 Packing Group

Description

FIPI is a potent and selective phospholipase D inhibitor. FIPI attenuate mercury-induced lipid signaling leading to protection against cytotoxicity in aortic endothelial cells. FIPI rapidly blocks in vivo PA production with subnanomolar potency. We were surprised to find that several biological processes blocked by 1-butanol are not affected by FIPI, suggesting the need for re-evaluation of proposed FIPI does inhibit PLD regulation of F-actin cytoskeleton reorganization, cell spreading, and chemotaxis, indicating potential utility for it as a therapeutic for autoimmunity and cancer metastasis.

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Telmisartan
2-[4-[[4-methyl-6-(1-methylbenzimidazol-2-yl)-2-propyl-benzimidazol-1-yl]methyl]phenyl]benzoic acid